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名稱
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Human TNF-alpha / TNFA Protein/重組人 TNF-alpha /
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規(guī)格
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20ug
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編號(hào)
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CZDB-006
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價(jià)格
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詢價(jià)
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中文名
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Human TNF-alpha / TNFA Protein/重組人 TNF-alpha /
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分子別稱
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TNF-alpha, TNF-a, Cachectin, DIF, TNFA, TNFSF2
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分子種屬
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Human |
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表達(dá)標(biāo)簽
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His，S
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表達(dá)宿主
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E. coli
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濃度
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> 95 % as determined by SDS-PAGE
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緩沖液
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Lyophilized from sterile PBS, pH 7.4
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存儲(chǔ)條件
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-70°C，應(yīng)避免反復(fù)凍融。
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基本描述
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Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. Two receptors, TNF-R1 (TNF receptor type 1; CD120a; p55/60) and TNF-R2 (TNF receptor type 2; CD120b; p75/80), bind to TNF-alpha. TNF-alpha protein is produced mainly by macrophages, and large amounts of this cytokine are released in response to lipopolysaccharide, other bacterial products, and Interleukin-1 (IL-1). TNF-alpha is involved in fighting against the tumorigenesis, thus, is regarded as a molecular insight in cancer treatment.
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